My laboratory has been interested in the structure, function, and evolution of the cholinesterases - acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). We have been particularly interested in the evolution of the molecular basis of substrate specificity of AChE and BChE, and the evolutionary appearance of the heterologous, tailed forms in craniates.
Esther: Analysis of sequences of superfamily of hydrolases homologous to cholinesterases.
Cholinesterases: (An on-line review by Kurt Giles)
The Amphioxus Project
Ciona intestinalis (sea squirt) genome project
Ensemble Browser for Ciona intestinalis
Gulf Specimens Marine Laboratory
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